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Research Officer/Research Assistant (Downstream Processing)

The Opportunity

Esco Lifesciences Group, is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 20 countries across North America, Europe and Asia.

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first introduced in 2017.

At Esco Aster Pte Ltd, we are a contract development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products and services at affordable prices.

The work we do creates a remarkable and lasting impact on our world. Join us as we redefine healthcare for the current and future generations to come.

Esco Aster.

One World. One Health.

The Scope

You will be part of Esco Aster’s Downstream Processing division and contribute to the company’s CDMO mission and objectives. You will perform research and process development activities for downstream activities and be involved in scaling up of operations for vaccines, therapeutic proteins and biologics. You will work in close coordination with internal and external stakeholders, clients and partners.

Primary work location: Ayer Rajah, Singapore

Reporting to: Lead Scientist

Job Responsibilities

  • Work in the CDMO services with the downstream R&D team and co-ordinate with manufacturing teams to scale up unit operations/ manufacturing at scale for vaccines, therapeutic proteins and biologics.
  • Plans, executes and assists experimental programs including data analysis required in the project.
  • Author protocols, technical reports and technology transfer documents with scientifically supported conclusions and recommendations.
  • Assessment and implementation of new processes, technologies in development scale, ultimately adapting to manufacturing operations.
  • Record and document data promptly and accurately maintaining data integrity.
  • Assisting in lab duties and administrative activities including procurement, inventory management, equipment maintenance, calibration etc.
  • Exercise scientific creativity and independent thought and be responsible for imparting knowledge in relation to limited skills or experimental expertise.
  • Perform all tasks in accordance with relevant regulations and site safety requirements.
  • Undertake tasks assigned by leaders as and when appropriate.


  • Degree or Diploma in Life Sciences/ Bioengineering/ Chemical Engineering/ Chemistry or related disciplines.
  • Minimum 2 years work experience in life-sciences or related laboratory working with the downstream purification of vaccines, therapeutic proteins and/or biologics.
  • Experience in different modes of preparative chromatography using purification skids (AKTA, NGC etc.).
  • Experience in filtration (NFF and TFF) unit operations and bioprocess integration.
  • Experienced in protein and molecular analyses, e.g. Western blot, qPCR, flow cytometry etc.
  • Knowledge of technical or commercial operations in the manufacture of biological molecules is desirable.
  • Take initiatives, research oriented, possess good communication and documentation skills and work well in a dynamic team environment.
  • Proven experience in laboratory operations, bench work, experimental design, method and data analysis.
  • Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
  • Able to work independently, self-starter, self-motivated and task oriented.
  • Good communication skills and able to openly communicate and escalate any relevant issues.
  • Strong team player, develop positive relationship with a strong set of interpersonal skills.
  • During the start-up phase of the team/facility, be willing to take on expanded role to set up workflow/processes as needed.

Apply now by submitting a Cover Letter and CV to [email protected].