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Are you a seasoned professional looking
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Electrical & Instrumentation and Calibration Engineer

The Opportunity

Esco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania. 

 

Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in 2017. 

 

Esco Aster is a contract research development and manufacturing organization founded and deeply rooted by scientists enabling fellow scientists to translate their bench work into commercially available products at affordable prices.

 

Our scientific work is in emerging and frontier biology utilizing cells as a final product or deriving products from cells which often we use cells as the factory to derive our target product. 

 

Our first commercial breakthrough success is Esco Aster is commercially first in class being first in the world to be certified for cultivated/cell-based meat to FSSC 22000 and by a competent food regulatory body.

 

We are first in the region to operate an end-to-end integrated full cell line creation/immortalization or engineered cell line, cell culture process development, analytical development for stem cells and exosomes with full cGMP Capabilities from Drug Substance and small-scale fill & finish for final Cell Therapy Product.

 

The work we do creates a remarkable and lasting impact on our world. We offer you an opportunity to be part of this exciting journey to own your career and firsthand exposure to new emerging modalities supporting translational sciences.

Join us as we redefine BioSolutions for One World and One Health for the current and future generations to come. 

 

Esco Aster. 

One World Biosolutions for One Health.

The Scope

You will be part of Esco Aster's Engineering team and contribute to the overall site mission and objectives. You are responsible for maintenance of plant electrical & instrumentation, site calibration activities, equipment fault troubleshooting and technical support on laboratory instrument. This position will involve the startup phase, liaising with the engineering firm on the design and construction of the facility, ensuring that the installations comply with safety guidelines, design intent and quality standards are met.

Primary work location: Ayer Rajah Crescent, Singapore

Reporting to: Head of Engineering

Job Responsibilities

  • Provide technical support on entire plant electrical and instrumentation including analyzers, maintenance diagnostics, calibration and reliability issues.
  • Assign and track site calibration schedule for relevant equipment and instruments to ensure no overdue, proper procedures are followed, quality of work and troubleshooting to resolve equipment problems during routine operation.
  • Lead and carry out site maintenance/calibration activities and co-ordinate with various end users if necessary.
  • Liaise and co-ordinate with external calibration service providers for routine calibration activities.
  • Develop procedures and work method statement to comply with regulatory codes, specifications, standards and guidelines for the routine maintenance and calibration activities.
  • Support and participate FAT, SATs, commissioning and validation activities.
  • Carry out and implement small improvement initiatives and engineering projects.
  • Participate, facilitate and review instrumentation discrepancies, root cause analyses and timely close out investigation report with follow up on all corrective actions and preventive actions.
  • Improve the plant's overall instrumentation reliability; including updating documentation, create maintenance procedures, loop drawings, P&ID's, schematics, wiring diagrams, improving the PM program, recommending spares and replacing obsolete equipment.
  • Provide ad-hoc technical support on manufacturing and laboratory equipment in timely manner.
  • Ensure maintenance and calibration services are delivered in a safe, compliant, reliable and efficient manner according to end user or customer expectations.
  • Interact with system owners and QA to assist in implementation of plant changes, including equipment additions, modifications and/or deletions.
  • Ensure GxP compliance for all maintenance and calibration activities.
  • Ensure timely review of all work order, closing of maintenance work order; initiate follow up work order and discrepancy notification as necessary.
  • Ensure all work activities are carried out according to site EHS procedures; and in compliance with EHS procedures/standards.
  • Ensure audit readiness by complying with effective standards, regulatory/statutory and GxP requirement to protect product and to prevent major compliance observation.
  • Implement preventive and corrective maintenance programs to maximize equipment availability and optimize life-cycle costs.
  • Conduct instrument criticality assessment with end user and setup instrument master data to establish calibration frequency and schedule in CMMS system.
  • Ensure the quality and accuracy of data and records of maintenance/calibration of the instruments.
  • Establish and maintain the proper stocking levels of parts and equipment required to provide maximum equipment uptime at the lowest possible costs.
  • Responsible for planning of maintenance activities with various departments to ensure resources, parts and vendors are on site per schedule for maintenance work.
  • Undertake tasks assigned by leaders as and when appropriate.

Requirements

  • Degree or Diploma in Electrical & Instrumentation, with a strong background in instrumentation and electrical systems.
  • Minimum of 5 years’ work experience in the pharmaceutical or related industry.
  • Minimum of 5 years' experience in E/I and calibration, with process instrumentation and analyzers in a pharmaceutical or chemical manufacturing facility and project start-up.
  • Must have working knowledge on various plant instrument and motor control including pH, flow, temperature, pressure, conductivity and mass measurements, load cells, control valves, panel schematic diagram, VFD's, AC and DC control methods.
  • Must have working knowledge on electrical system and high voltage equipment like transformer, switch gear, diesel power generator, electric heater, busbar with distribution panel and UPS.
  • Familiar with CMMS system in terms of work order execution, PM/calibration schedule and tracking. CMMS software with Blue Mountain RAM software is highly preferred.
  • Familiar and understand GxP requirement for routine maintenance and calibration.
  • Experience with start-up, commissioning and qualification of various process equipment, including requirements for documentation and testing.
  • Able to work independently, self-starter, self-motivated and task oriented.
  • Good communication skills and able to openly communicate and escalate any relevant issues.
  • A strong team player and customer orientated to work with both internal and external stakeholders.
  • During the start-up phase of the facility, be willing to take on expanded role to set up the team and workflow/processes as well as expanded scope as needed.
  • Excellent oral and written communication skills with high computer literacy
  • Needs to be resourceful in sourcing out materials and parts required equipment setup or repair.

Minimum Requirements

  • Ability to read, analyze and interpret scientific data and publications
  • Ability to author or review protocols, technical reports and technology transfer documents.
  • Ability to author or review standard operating procedures and other related documents.
  • Ability to define problems, collect data, establish facts, and draw conclusions.
  • Ability to focus
  • Repetitive motions due to certain laboratory techniques

Apply now by submitting a Cover Letter and CV to [email protected].