About Esco Aster

Master Cell / Microbial Banking

Our cGMP-compliant cell bank can preserve a large volume of cell lines, microbial cells, and other biologics for the manufacture of commercially available therapeutics.

We ensure that all samples collected either on the field or on our biobank are carefully processed and transported using the best techniques for preservation.

Clinical Trial Material

We take part on several preclinical to clinical testing to determine efficacy of medical drugs and substances.

Our dedicated scientist can serve as your partner from lead optimization to commercialization for your next advanced therapy.

cGMP Process Development

Apart from process equipment and turnkey facilities, we offer process development to support client's specific needs and requirements for cell culture process development and optimization. This includes cell culture medium optimization, seed preparation process development, and system layout and process integration.

Process Transfer

We are able to provide fast, efficient and robust vaccine technology transfer with single-use solutions, predictive process control, process scale up/scale down, complexity reduction, and process validation.

Plasmid DNA Manufacturing Services

We offer CDMO services to manufacture various grades of plasmid DNA for preclinical, clinical and commercial production. We maintain GMP standards from the starting material to the final drug products in our Plasmid DNA production process.

Extracellular Vesicles

Extracellular vesicles are secreted by many cells, of which the common ones are Mesenchymal Stromal Cells, Pericytes, CAR-T cells, human primary bronchial epithelial cell, epithelial cells, EBV(Epstein-Barr virus)-immortalized B cells, HUVECs (Human umbilical vein endothelial cells) Leukocytes, platelets, cancer cells and even neural cells. They are classified into three groups depending on their size.

Cell Line Creation

We specialize and are best-in-class in accelerated adherent cell line creation and development in conjunction with our adherent cell banking, characterization, testing and storage services for your various applications.

Cell Therapy

We leveraged on the Tide Motion bioreactors to establish a robust and scalable platform using macrocarriers to meet the demands for future clinical therapies.

Gene Therapy

With the use of our in-house bioreactors, viral vectors can be produced at a scalable and affordable rate for your gene therapy applications.

Human Vaccines

We are committed in providing vaccines that are accessible and affordable to the Asian and global population. It does so through its proprietary Tide Motion® platform that can rapidly speed up the manufacturing process of Viral vaccines.

Viral Vectors

Our state-of-the-art facilities and experts are within easy reach in order to assist in all areas of viral vector design and construction, as well as the generation of these viral vectors in high titer.

Strain Engineering / Development Services

Leveraging the market demand for rapid biologics development, we offer a strain development platform with state-of-the-art technology of random mutagenesis using Atmospheric Room Temperature Plasma (ARTP) technology and high-throughput and parallel screening of strains using Microbial Microdroplet Culture (MMC) system.

Combining these technologies, we can eliminate the limitations of conventional screening and save enormous time, labour, and cost.

Lipid Nanoparticle Development and Formulation Services

We can help develop your LNP formulations with our expert team of formulation scientists and provide contract manufacturing service with our fill-and-finish systems in an advanced facility to produce your product at large-scale quantities for clinical trials. We have the speed, reliability and expertise to collaborate with you through a turnkey solution from development to manufacturing .